The U.S. Supreme Court case Kansas City Southern Railway Company v. Jones, Administrator in 1927 revolved around a dispute over the liability of an employer for an employee's death due to negligence under the Federal Employers' Liability Act (FELA). The plaintiff, Jones, was the administrator of a deceased railway worker who died while on duty as a result of alleged negligence by his co-workers and supervisors. The defendant, Kansas City Southern Railway Company argued that it should not be held liable because there was no evidence proving its direct involvement or negligence leading to the accident. However, after reviewing previous cases and interpretations of FELA provisions regarding employers’ responsibility for employees' safety at work places, the court ruled in favor of Jones stating that even if there is no direct fault from employer’s side but if any injury occurs due to negligent acts by fellow workers during their employment then company can be held responsible under FELA.

In the dissenting opinion for Kansas City Southern Railway Company v. Jones, Justice Stone disagreed with the majority's ruling that a state could impose its own laws on interstate commerce in cases where federal law did not explicitly regulate it. He argued that this interpretation of the Commerce Clause was too narrow and would allow states to interfere with interstate commerce in ways that could be detrimental to national interests. He also contended that allowing each state to set its own rules for matters involving interstate commerce would create confusion and inconsistency, as different states might have conflicting regulations. Furthermore, he believed this decision undermined Congress' authority over interstate commerce by implying it needed to specifically legislate every aspect of it or risk losing control to individual states.