The Polar Ice Cream & Creamery Co. v. Andrews case in 1963 involved the Florida Milk Commission and its regulations on milk pricing, which were challenged by the Polar Ice Cream company as unconstitutional. The Supreme Court ruled that these regulations did not violate the Equal Protection Clause of the Fourteenth Amendment or Due Process Clause because they served a legitimate state interest to protect consumers from price manipulation and ensure an adequate supply of wholesome milk products for all citizens. The court also found no evidence that these laws unfairly discriminated against out-of-state businesses since they applied equally to all producers selling within Florida's borders, regardless of their location.

The dissenting opinion in the case of Polar Ice Cream & Creamery Co. v. Andrews et al., argued that the Florida Milk Commission's price-fixing scheme was not a violation of the Equal Protection Clause, as it served a legitimate state interest and did not arbitrarily discriminate against any particular group. The justices believed that states have broad powers to regulate economic activities within their borders, including setting minimum prices for certain goods or services to protect public welfare and prevent unfair competition. They contended that such regulations should be upheld unless they are clearly unreasonable or arbitrary, which they didn't believe was true in this case. Therefore, they disagreed with the majority's decision to strike down Florida's milk pricing laws on constitutional grounds.