In the case of National Labor Relations Board v. Gamble Enterprises, Inc., 1952, the U.S Supreme Court ruled in favor of the National Labor Relations Board (NLRB). The NLRB had accused Gamble Enterprises, a retail grocery chain based in Mississippi, of unfair labor practices. These included interfering with its employees' rights to form and join labor unions as well as refusing to bargain collectively with their chosen representative. The company argued that it was not engaged in interstate commerce and therefore outside the jurisdiction of federal law governing such matters. However, evidence showed that a significant portion of goods sold by Gamble were transported across state lines which brought them under federal regulation according to previous court rulings on similar cases. Thus, the Supreme Court upheld lower courts' decisions affirming NLRB's authority over this matter and ordered Gamble Enterprises to cease its unlawful activities against unionization efforts among its workers.

The dissenting opinion in the case of National Labor Relations Board v. Gamble Enterprises, Inc., argued that the majority's decision to enforce a cease and desist order against Gamble Enterprises for unfair labor practices was unjustified. The dissent contended that there was insufficient evidence to prove that Gamble had interfered with its employees' rights to engage in collective bargaining or other protected activities under Section 7 of the National Labor Relations Act. They also disagreed with the majority's interpretation of "employer" under Section 2(2) of the Act, arguing it should not include those who have no direct control over employment conditions but merely influence them indirectly through economic pressure. Furthermore, they believed this broad interpretation could potentially infrive on employers' First Amendment rights by limiting their freedom to express opposition towards unions without fear of legal repercussions.