In the case of Missouri Pacific Railroad Company v. Aeby, the U.S Supreme Court ruled in favor of the railroad company. The dispute arose when a train owned by Missouri Pacific collided with a truck driven by Aeby at an intersection where there were no warning signals or barriers to prevent such accidents. As a result, Aeby suffered severe injuries and sued for damages on grounds that it was due to negligence on part of the railway company for not having proper safety measures in place. However, upon review, it was found that despite lack of warnings or barriers at this particular crossing point, other factors contributed significantly towards accident including poor visibility conditions and reckless driving from Mr.Aeby's side as he failed to stop before proceeding across tracks even though he knew about presence of rail line ahead. Therefore,the court concluded that while absence of safety precautions might have been contributory factor,it wasn't sole cause behind collision hence liability couldn't be imposed solely on railroad company.

In the dissenting opinion for the case Missouri Pacific Railroad Company v. Aeby, it was argued that the court majority erred in its interpretation of federal law and overstepped its jurisdiction by interfering with state laws governing railroad operations. The dissenting justices believed that there was no violation of federal law as claimed by Missouri Pacific Railroad Company because they were not denied a fair return on their property or deprived of due process rights under the Fourteenth Amendment. They contended that states have inherent power to regulate businesses within their borders, including setting reasonable rates for services provided by public utilities like railroads. Therefore, they disagreed with the majority's decision to overturn a rate set by Kansas regulatory authorities as being confiscatory and violating constitutional rights of railroads without providing substantial evidence supporting such claims.